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Urinary fumonisin B1 and estimated fumonisin intake in women from high- and low-exposure communities in Guatemala.

Permanent URL:
http://handle.nal.usda.gov/10113/58743
File:
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Abstract:
Scope: Fumonisin (FB) intake can be high when maize is a dietary staple. We determined 1) urinary FB (UFB) in women consuming maize in high and low exposure communities in Guatemala, 2) the FB levels in maize, 3) the stoichiometric relationship between UFB and FB intake, and 4) the relative excretion of UFB1, UFB2 and UFB3. Methods and results: Urine and maize were analyzed for FB for one year in three departamentos. Maize consumption was estimated by questionnaire. FB1, FB2 and FB3 were detected in 100% of maize samples. FB1 in maize and urine were significantly higher in Jutiapa compared to Chimaltenango or Escuintla. The total FB intake paralleled UFB1 in a dose-dependent manner but UFB1 was present in much higher levels than UFB2 or UFB3 compared to levels in maize. Conclusions: In Jutiapa agro-ecological conditions favor FB production and UFB1 was significantly higher than in Chimaltenango or Escuintla. UFB1 mirrored the levels of estimated FB intake in all three departamentos, and when UFB1 was >0.5 ng/ml women were likely to exceed 2 µg/kg b.w./day regardless of how FB intake was estimated. While UFB2 and UFB3 were occasionally detected, the results confirmed that FB1 is preferentially excreted in urine.
Author(s):
Olga Torres , Jorge Matute , Janee Gelineau-van Waes , Joyce R. Maddox , Simon G. Gregory , Allison E. Ashley-Koch , Jency L. Showker , Nicholas C. Zitoner , Kenneth A. Voss , Ronald T. Riley
Subject(s):
corn , excretion , food contamination , food intake , fumonisin B1 , urine , women , Guatemala
Note:
USDA Scientist Submission
Source:
Molecular nutrition & food research 2014 v.58 no.5
Language:
English
Year:
2014
Collection:
Journal Articles, USDA Authors, Peer-Reviewed
Rights:
Works produced by employees of the U.S. Government as part of their official duties are not copyrighted within the U.S. The content of this document is not copyrighted.