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Chromium picolinate supplementation in women: effects on body weight, composition, and iron status

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Objective: This study tested the hypothesis that supplementation of chromium picolinate (CrPic), 200 μg Cr/d, compared with an equivalent amount of picolinic acid (1720 μg) in CrPic and placebo, decreases body weight, alters body composition, and reduces iron status of women fed diets of constant energy and nutrients. Methods: We fed 83 women nutritionally balanced diets, used anthropometry and dual x-ray absorptiometry to assess body composition, and measured serum and urinary Cr and biochemical indicators of iron status before and serially every 4 wk for 12 wk in a double-blind, randomized trial. Results: CrPic supplementation increased (P < 0.0001) serum Cr concentration and urinary Cr excretion compared with picolinic acid and placebo. CrPic did not affect body weight or fat, although all groups lost (P < 0.05) weight and fat; it did not affect fat-free, mineral-free mass or measurements of iron status. Conclusion: Under conditions of controlled energy intake, CrPic supplementation of women did not independently influence body weight or composition or iron status. Thus, claims that supplementation of 200 μg of Cr as CrPic promotes weight loss and body composition changes are not supported.
Lukaski, Henry C. , Siders, William A. , Penland, James G.
women , weight control programs , chromium , dietary supplements , picolinic acid , weight loss , body fat , lean body mass , body composition , fat free mass , nutritional status , lifestyle
p. 187-195.
Includes references
Nutrition 2007 Mar., v. 23, issue 3
Journal Articles, USDA Authors, Peer-Reviewed
Works produced by employees of the U.S. Government as part of their official duties are not copyrighted within the U.S. The content of this document is not copyrighted.