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A LysM Receptor-Like Kinase Plays a Critical Role in Chitin Signaling and Fungal Resistance in Arabidopsis

Permanent URL:
http://handle.nal.usda.gov/10113/27070
Abstract:
Chitin, a polymer of N-acetyl-D-glucosamine, is found in fungal cell walls but not in plants. Plant cells can perceive chitin fragments (chitooligosaccharides) leading to gene induction and defense responses. We identified a LysM receptor-like protein (LysM RLK1) required for chitin signaling in Arabidopsis thaliana. The mutation in this gene blocked the induction of almost all chitooligosaccharide-responsive genes and led to more susceptibility to fungal pathogens but had no effect on infection by a bacterial pathogen. Additionally, exogenously applied chitooligosaccharides enhanced resistance against both fungal and bacterial pathogens in the wild-type plants but not in the mutant. Together, our data indicate that LysM RLK1 is essential for chitin signaling in plants (likely as part of the receptor complex) and is involved in chitin-mediated plant innate immunity. The LysM RLK1-mediated chitin signaling pathway is unique, but it may share a conserved downstream pathway with the FLS2/flagellin- and EFR/EF-Tu-mediated signaling pathways. Additionally, our work suggests a possible evolutionary relationship between the chitin and Nod factor perception mechanisms due to the similarities between their potential receptors and between the signal molecules perceived by them.
Author(s):
Wan, Jinrong , Zhang, Xue-Cheng , Neece, David , Ramonell, Katrina M. , Clough, Steve , Kim, Sung-yong , Stacey, Minviluz G. , Stacey, Gary
Subject(s):
Arabidopsis , plant proteins , protein kinases , disease resistance , chitin , signal transduction , fungal diseases of plants , bacterial diseases of plants
Format:
p. 471-481.
Note:
Includes references
Source:
Plant cell 2008 Feb., v. 20, no. 2
Language:
English
Publisher:
American Society of Plant Biologists
Year:
2008
Collection:
Journal Articles, USDA Authors, Peer-Reviewed
File:
Download [PDF File]
Rights:
Works produced by employees of the U.S. Government as part of their official duties are not copyrighted within the U.S. The content of this document is not copyrighted.